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Showing posts with the label Pharmaceutical Chemistry - Inorganic

Ferrous Sulphate

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  H A E M A t I N I C s Ferrous Sulphate (FeSO₄.7H₂O) molecular weight = 278 Not less than 98% not more than 103.3 N  PREPARATIONS It is obtained by dissolving iron in excess of dil. H₂SO ₄ After the effervescence stops ---> liquid is filtered, concentrated and cooled. The green crystals are formed  In all this operations undue exposure to air is prevented, because ferrous sulphate is oxidized readily on exposure to moist air and the crystal gets coated with brownish yellow ferric sulphate. Fe +  H₂SO ₄  ------>  FeSO₄ +  H₂ ↑ PROPERTIES Occurs in green crystals or crystalline powders, Astringent taste, Effloresces in dry air, In air, oxidised to ferric salt of brownish yellow color, Soluble in water, Insoluble in alcohol, When heated, decomposes to yield Ferric Oxide, Sulphur dioxide, and sulphuric acid. 2( FeSO₄.7H₂O ) + Heat -------> Fe₂O₃ + SO₂ +  H₂SO₄ + 13 H₂O Ferrous sulphate reduces the salts of silver and gold to their ...

Haematinics

H A E M A t I N I C s They   are the agents used for formation of blood to treat various types of anemia.  These include: Iron, Vitamin B 12 and Folic Acid. There are mainly two drugs or chemical that are used as haematinics : Ferrous Sulphate (FeSO₄) Ferrous Gluconate (C₁₂H₂₂O₁₄Fe.2H₂O)

Buffer Stability

  Buffer Stability --> Buffer Stability is also known as the Buffer Capacity, buffer effectiveness, etc. --> It is defined as the amount of acid or base that must be added to buffer to produce a unit change of pH. Hence,                                           β  =   (   Δ A or    ΔB)/(   Δ pH)               where,  β = buffer stability, Δ A or    ΔB = amount of acid or base added, Δ pH = unit change of pH                                                                                                                 ...